Medication Card contribution guide

• Medications can be found in this page here and are also accessible through popups

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  Rx

  Bilastine

  Brand Names: Blexten

  Routes: 10 or 20mg tab, 2.5mg/ml liq (uncommon)

  MoA: 2nd gen H1 receptor antagonist

  Half-life: ~15 hours

  Time to peak action: ~1h, rapid absorption

  Doses:

  • CSU, AR:
    • 20mg PO OD to QID (ages ≥12)
    • 10mg PO OD to QID (ages 4-11)

  Cost: ~$1.1 CAD / 20mg tab (ON)

  Coverage: ON (ODB)

  Age Group: ages ≥4

  Pregnancy: Avoid (not enough data)

  Contraindications: Hypersensitivity, QT prolongation or history of torsades

  Common SEs: QT prolongation (at 100mg ODx4, max mean increase 6ms); drowsiness/headache ~4%[D], ~3%[P]; abdo pain 3%[D], 3%[P]

  Severe SEs: Torsades (extremely rare; only 1 case reported in monograph post-market reactions)

  Monograph Links:

  • Bilastine (2021 - 1)

  Abbr.

  CSU-chronic spontaneous urticaria; AR-allergic rhinitis

  Pearls

  • Theoretically does not cross BBB; less sedating than other AHs

  • No renal adjustments needed; minimal data with hepatic impairment but not expected to cause issues

  • Going beyond OD is technically off-label

  • Take without food or juice otherwise absorption impaired

• The goal is to provide cards that are succinct and relevant, not a deep dive – the user can look at the monograph if needed for more detail

• As such, there's a relatively standardized structure/format for medications

  • The editors will deal with the categories section
  • Monographs will be statically hosted and linked. Include a link for the monograph in your draft file so it can be uploaded to the site (it should come from a government site!!)

# All sections accept HTML aside from the pearls, which accepts markdown format
[template_med]
# [medname] must be formatted as {generic (hyphenate if combination)} with {_route} if dramatically different from oral.
# for example: [budesonide_inhaler] because the oral form is used for EoE.
# similarly, [fluticasone-furoate_inhaler] - note the hyphenation used between the drug combos.
draft = false # if false, the medication card will be rendered with a WIP sign
categories = ["testcategory"] # check with the editors for the proper category
brand_names = ["brandnameA", "brandnameB"]
cost = [
  { province = "ON", price = "~$X CAD / Ymg tab" },
  { province = "BC", price = "~$X CAD / Ymg tab" },
]
coverage = [
  { province = "ON", details = "enter details" }, # ie. ODB
  { province = "BC", details = "enter details" },
]
otc = "yes" # only 'yes' or 'no' or 'both' allowed
moa = "Insert MoA" # should be BRIEF
half_life = "~X hours"
peak_action = "Optional" # how long it takes for the medication to have its intended or maximal effect
routes = "Xmg tab; Xmg/ml liq" # include doses available for each route ie. "10/20mg tab; 2.5mg/ml liq"
doses = [
  { indication = "diseaseA", dose = "Zmg OD", notes = "ages 3-11" }, # ages should be listed as "ages X-Y", or "ages ≥X"
  { indication = "diseaseA", dose = "Zmg OD", notes = "ages ≥12; CrCl < 30" }, # separate different notes with semi-colon
  { indication = "diseaseB", dose = "Zmg BID", notes = "ages ≥18; >25kg" }, # just list weights out
]
age_group = "insert age group" # just list the ages it has been used in; this is a broad overview. you'll go into the specific ages for separate indications in the doses section
pregnancy = "insert information, can link to data/links if need be"
contraindications = "insert"
side_effects.common = "insert" # common is ≥1%; if severe list below instead; if possible list out drug vs placebo rates from the monograph, ie. "Drowsiness 3-9%[D], 2-5%[P];"
side_effects.severe = "insert" # list the probability for these
monograph_links = [
  "/monographs/example_2025_1.pdf",
] # Filenames should be formatted as: genericname_2016_1, where the year is of the last revision and the last number is if there are multiple monographs that year for that drug
abbreviations = "" # ie: "AR-allergic rhinitis; CRS-chronic rhinosinusitis; AI-adrenal insufficiency"
pearls = [
  "Insert pearl here",
]

Here is an example:

[bilastine]
draft = false
categories = ["2G antihistamine"]
brand_names = ["Blexten"]
cost = [{ province = "ON", price = "~$1.1 CAD / 20mg tab" }]
coverage = [{ province = "ON", details = "ODB" }]
otc = "no"
moa = "2nd gen H1 receptor antagonist"
half_life = "~15 hours"
peak_action = "~1h, rapid absorption"
routes = "10/20mg tab, 2.5mg/ml liq (uncommon)"
doses = [
  { indication = "CSU, AR", dose = "20mg PO OD to QID", notes = "ages ≥12" },
  { indication = "CSU, AR", dose = "10mg PO OD to QID", notes = "ages 4-11" },
]
age_group = "ages ≥4"
pregnancy = "Avoid (not enough data)"
contraindications = "Hypersensitivity, QT prolongation or history of torsades"
side_effects.common = "QT prolongation (at 100mg ODx4, max mean increase 6ms); drowsiness/headache ~4%[D], ~3%[P]; abdo pain 3%[D], 3%[P]"
side_effects.severe = "Torsades (extremely rare; only 1 case reported in monograph post-market reactions)"
monograph_links = ["/monographs/bilastine_2021_1.pdf"]
abbreviations = "CSU-chronic spontaneous urticaria; AR-allergic rhinitis"
pearls = [
  "Theoretically does not cross BBB; less sedating than other AHs",
  "No renal adjustments needed; minimal data with hepatic impairment but not expected to cause issues",
  "Going beyond OD is technically off-label",
  "Take without food or juice otherwise absorption impaired",
]

How it'll actually look: