PEN-FAST

Joshua Yu November 10, 2024 #tools #drug allergy

A severe cutaneous adverse drug reaction includes Stevens-Johnson syndrome, toxic epidermal necrolysis, DRESS, or acute generalized exanthematous pustulosis. Acute interstitial nephritis, drug induced liver injury, serum sickness and isolated drug fever are not counted.

PEN-FAST

F - Five years or less since reaction
A - Anaphylaxis or angioedema
S - Severe cutaneous adverse reaction
T - Treatment recieved for reaction (or unsure)

CALCULATED RISK:

Source: Trubiano JA, Vogrin S, Chua KYL et al. Development and Validation of a Penicillin Allergy Clinical Decision Rule. JAMA Internal Med. Published March 16, 2020. doi:10.1001/jamainternmed.2020.0403